Ncert Exercises & Solutions

23. Complete the equation for reductive amination ..........

$+ {NH}_{4}^{+} + NADPH \overset{?}{\to} glutamate + H_{2} O + NADP$

Reductive Amination Ammonia combines with a keto acid (like

α

- ketoglutaric acid or oxaloacetic acid) to form amino acid in presence of a reduced cognenne (NADH,NADPH) and enzyme dehydrogenase (e.g., glutamate dehydrogenase, aspartate dehydrogenase).

\begin{array}{l} α - ketoglutaric acid + {NH}_{4}^{+} + NAD (P) H \to_{dehydrogenase}^{Glutamate} Glutamate + H_{2} O + NAD (P) \end{array}

Oxaloacetic acid + {NH}_{4}^{+} + NAD (P) H \to_{dehydrogenase}^{Aspartate} Asparatate + H_{2} O + NAD (P)

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