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Regarding Mendelian disorders :
| 1. | Color blindness is more common in the females of the species. |
| 2. | Sickle cell anemia occurs due to the substitution of valine by glutamic acid in the globin chain of haemoglobin. |
| 3. | Individuals affected by phenylketonuria lack an enzyme that converts tyrosine to phenylalanine. |
| 4. | Thalassemia is inherited as an autosomal recessive trait. |
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