Match the following columns and select the correct option.
| Column-I | Column-II | ||
| a. | Bt cotton | (i) | Gene therapy |
| b. | Adenosine deaminase deficiency | (ii) | Cellular defense |
| c. | RNAi | (iii) | Detection of HIV infection |
| d. | PCR | (iv) | Bacillus thuringiensis |
| a | b | c | d | |
| 1. | (iii) | (ii) | (i) | (iv) |
| 2. | (ii) | (iii) | (iv) | (i) |
| 3. | (i) | (ii) | (iii) | (iv) |
| 4. | (iv) | (i) | (ii) | (iii) |
When gene targeting involving gene amplification is attempted in an individual's tissue to treat disease, it is known as:
| 1. | Molecular diagnosis | 2. | Safety testing |
| 3. | Biopiracy | 4. | Gene therapy |
The Adenosine deaminase deficiency results into:
| 1. | Digestive disorder | 2. | Addison's disease |
| 3. | Dysfunction of Immune system | 4. | Parkinson's disease |
| Assertion (A): | Gene therapy is a method of treating a disorder but cannot cure it. |
| Reason (R): | Cells are drawn from a patient and the functional gene is introduced into these cells and transferred back to the patient. |
| 1. | Both (A) and (R) are True and (R) is the correct explanation of (A). |
| 2. | Both (A) and (R) are True and (R) is not the correct explanation of (A). |
| 3. | (A) is True but (R) is False. |
| 4. | (A) is False but (R) is True. |
| 1. | the absence of plasmids. |
| 2. | mutant alleles. |
| 3. | holes in the DNA made by viruses. |
| 4. | the lack of copy DNA. |
| List-I | List-II | ||
| (A) | Gene therapy | (I) | Separation of DNA fragments |
| (B) | RNA interference | (II) | Diagnostic test for AIDS |
| (C) | ELISA | (III) | Cellular defense |
| (D) | Gel Electrophoresis | (IV) | Allows correction of a gene defect |
| Options: | (A) | (B) | (C) | (D) |
| 1. | IV | I | II | III |
| 2. | IV | II | III | I |
| 3. | IV | III | II | I |
| 4. | IV | III | I | II |
Which kind of therapy was given in 1990 to a four-year-old girl with Adenosine Deaminase (ADA) deficiency?
1. Gene therapy
2. Chemotherapy
3. Immunotherapy
4. Radiation therapy
The first clinical gene therapy was given for treating:
1. Chickenpox
2. Rheumatoid arthritis
3. Adenosine deaminase deficiency
4. Diabetes mellitus