| 1. | acetylcholine is released |
| 2. | active sites on the actin filaments are exposed |
| 3. | filaments slide past one another, and the muscle fiber shortens |
| 4. | myosin is activated |
The following events occur during a reflex response to a person placing a hand on a hot object.
1 Myosin binding sites on actin filaments uncovered.
2 ADP and phosphate ion released from myosin head.
3 Sodium voltagegated channels open.
4 Myosin head detaches from the binding sites on actin.
5 Calcium ions released by sarcoplasmic reticulum.
Which of the following options places four of these events in the correct order (from left to right)?
1. 3, 5, 4, 2
2. 5, 2, 1, 4
3. 1, 2, 4, 3
4. 5, 1, 2, 4
| 1. | Sarcomere does not shorten | 2. | A band remains the same |
| 3. | A, H and I bands shorten | 4. | Actin filaments shorten |
During muscular contraction, which of the following events occur?
| (a) | 'H' zone disappears |
| (b) | 'A' band widens |
| (c) | 'I' band reduces in width |
| (d) | Myosin hydrolyzes ATP, releasing the ADP and Pi |
| (e) | Z-lines attached to actins are pulled inwards |
Choose the correct answer from the options given below:
1. (b), (c), (d) and (e) only
2. (b), (d), (e) and (a) only
3. (a), (c), (d) and (e) only
4. (a), (b), (c) and (d) only
Sliding filament theory can be best explained as:
| 1. | when myofilaments slide past each other, actin filaments shorten while myosin filament does not shorten |
| 2. | actin and myosin filaments shorten and slide past each other |
| 3. | actin and myosin filaments do not shorten but rather slide pass each other |
| 4. | when myofilaments slide past each other, myosin filaments shorten while actin filaments do not shorten |
| 1. | binds to troponin to remove the masking of active sites on actin for myosin. |
| 2. | activates the myosin ATPase by binding to it. |
| 3. | detaches the myosin head from the actin filament. |
| 4. | prevents the formation of bonds between the myosin cross bridges and the actin filament. |
| 1. | Actin and myosin filaments slide over each other to increase the length of the sarcomere. |
| 2. | Length of A–band does not change. |
| 3. | I–band increases in length |
| 4. | The actin filaments slide away from A–band resulting in shortening of sarcomere |
| 1. | binds to the actin and myosin and makes them work together. |
| 2. | breaks apart ATP to ADP and P. |
| 3. | removes the tropomyosin block. |
| 4. | causes the release of acetylcholine. |
| 1. | the myosin head binds to the exposed active sites on actin utilising the energy from ATP hydrolysis |
| 2. | the myosin head binds to the exposed active sites on actin and then the ATP binds to its site on myosin head |
| 3. | the actin binds to the exposed active sites on myosin head utilising the energy from ATP hydrolysis |
| 4. | the actin binds to the exposed active sites on myosin head and then the ATP binds to its site on actin |