Calcium ions are released from the sarcoplasmic reticulum. What happens next?
1. acetylcholine is released
2. active sites on the actin filaments are exposed
3. filaments slide past one another, and the muscle fiber shortens
4. myosin is activated
Subtopic:  Sliding Filament Theory |
 82%
Level 1: 80%+
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The following events occur during a reflex response to a person placing a hand on a hot object.

1 Myosin binding sites on actin filaments uncovered.
2 ADP and phosphate ion released from myosin head.
3 Sodium voltage­gated channels open.
4 Myosin head detaches from the binding sites on actin.
5 Calcium ions released by sarcoplasmic reticulum.

Which of the following options places four of these events in the correct order (from left to right)?

1.  3, 5, 4, 2

2.  5, 2, 1, 4

3.  1, 2, 4, 3

4.  5, 1, 2, 4

Subtopic:  Sliding Filament Theory |
 59%
Level 3: 35%-60%
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During muscle contraction in humans the:
1. Sarcomere does not shorten 2. A band remains the same
3. A, H and I bands shorten 4. Actin filaments shorten
Subtopic:  Sliding Filament Theory |
 85%
Level 1: 80%+
NEET - 2013
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During muscular contraction, which of the following events occur?

(a) 'H' zone disappears
(b) 'A' band widens
(c) 'I' band reduces in width
(d) Myosin hydrolyzes ATP, releasing the ADP and Pi
(e) Z-lines attached to actins are pulled inwards

Choose the correct answer from the options given below:

1. (b), (c), (d) and (e) only

2. (b), (d), (e) and (a) only

3. (a), (c), (d) and (e) only

4. (a), (b), (c) and (d) only

Subtopic:  Sliding Filament Theory |
 82%
Level 1: 80%+
NEET - 2021
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Sliding filament theory can be best explained as:

1. when myofilaments slide past each other, actin filaments shorten while myosin filament does not shorten
2. actin and myosin filaments shorten and slide past each other
3. actin and myosin filaments do not shorten but rather slide pass each other
4. when myofilaments slide past each other, myosin filaments shorten while actin filaments do not shorten
Subtopic:  Sliding Filament Theory |
 52%
Level 3: 35%-60%
NEET - 2015
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Calcium is important in skeletal muscle contraction because it:
1. binds to troponin to remove the masking of active sites on actin for myosin.
2. activates the myosin ATPase by binding to it.
3. detaches the myosin head from the actin filament.
4. prevents the formation of bonds between the myosin cross bridges and the actin filament.
Subtopic:  Excitation Contraction Coupling I | Sliding Filament Theory | Muscle Contraction: Other Considerations |
 87%
Level 1: 80%+
NEET - 2018
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According to the sliding filament theory:
1. Actin and myosin filaments slide over each other to increase the length of the sarcomere.
2. Length of A–band does not change.
3. I–band increases in length
4. The actin filaments slide away from A–band resulting in shortening of sarcomere
Subtopic:  Sliding Filament Theory |
 74%
Level 2: 60%+
NEET - 2022
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Calcium released into the sarcoplasm during muscle contraction:
1. binds to the actin and myosin and makes them work together.
2. breaks apart ATP to ADP and P.
3. removes the tropomyosin block.
4. causes the release of acetylcholine.
Subtopic:  Sliding Filament Theory |
 60%
Level 2: 60%+
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A skeletal muscle motor unit is best described as:
1. a section of myofibrils from Z lines to Z lines
2. one nerve fiber and all the muscle fibers innervated by that nerve fiber
3. all of the nerves that unite to make a whole muscle contract
4. all of the fascicles innervated by several neurons
Subtopic:  Sliding Filament Theory | Muscle Contraction: Other Considerations |
 66%
Level 2: 60%+
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To form a cross bridge, during muscle contraction:
1. the myosin head binds to the exposed active sites on actin utilising the energy from ATP hydrolysis
2. the myosin head binds to the exposed active sites on actin and then the ATP binds to its site on myosin head
3. the actin binds to the exposed active sites on myosin head utilising the energy from ATP hydrolysis
4. the actin binds to the exposed active sites on myosin head and then the ATP binds to its site on actin
Subtopic:  Sliding Filament Theory |
 72%
Level 2: 60%+
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